The Defenders - Iron Fist, Jessica Jones, Luke Cage and Daredevil, protectors of the people - are in a desperate struggle to keep New York City safe in the wake of the power vacuum caused by the Kingpin's absence and the all-out street war that results! So what could make things even worse for our team of harried heroes? Would you believe - Deadpool? The Kingpin's kingdom is up for grabs, and the streets of Marvel will burn as every major underworld figure makes a play to be the next kingpin of crime! Unfortunately for them, this is exactly why the Defenders have gathered - to make our streets a safer place! But bad press is about to have a disastrous impact on Luke's and Jessica's lives. And how exactly does Diamondback know so much about the Defenders?